Tag: Chagas Disease

Research led by Brazilian scientists determined that the genetic mutation may be linked to disorders in patients with Chagas disease. This condition is caused by Chagas disease and causes the esophagus to become inflamed. For researchers, the survey findings may inspire new treatments for people with this condition. Observations indicate that in carriers of these mutations, increased production of an inflammatory mediator known as IFN-gamma leads to dysfunction of mitochondria (responsible for energy generation) in neurons. Thus, the degeneration of neurons present in the wall of the esophagus will contribute to...